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严格精子形态分析正常形态精子百分率对常规IVF受精率的影响研究 被引量:10

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摘要 目的:探讨人常规体外受精(in vitro fertilization,IVF)中严格精子形态分析正常形态精子百分率与受精率之间的关系,分析正常形态精子百分率对常规1VF受精率的影响。方法:IVF前3个月内分析拟行常规IVF的精液标本156人份,进行常规精液分析、严格精子形态分析。观察156个常规IVF周期,按正常形态精子百分率分为3组:A组,≥5%~≤10%,45周期;B组,>10%~<15%,68周期;C组,≥15%,43周期。比较各组间的MⅡ卵受精率。结果:A、B、C组相对应的各组卵子受精率分别为78.88%、86.24%、92.13%,各组间比较差异有统计学意义(P<0.05)。除在A组中出现1周期,获MⅡ卵5个,卵子全部不受精外,其余各组各周期受精率均≥30%。结论:在常规IVF中,精子的形态对卵子的受精率有着明显的影响,在精液精子密度≥20×106/mL,活动率≥5%,a+b级精子≥5%;或精子密度>5×106~<20×106/mL,同时a+b级运动精子>20%条件下,正常形态精子≥5%,可选择常规IVF治疗;正常形态精子百分率高,卵子受精率亦较高。
出处 《广西医科大学学报》 CAS 2010年第1期92-93,共2页 Journal of Guangxi Medical University
基金 南宁市科技攻关与新产品试制项目课题(No.20060172c)
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参考文献5

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二级参考文献11

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