大剂量口服1,25(OH)_2D_3冲击治疗腹透患者血清甲状旁腺素(1～84)异常的观察

Observation of PTH(1～84)in Continuous Ambulatory Peritoneal Dialysis Patients with Oral 1, 25(OH),D, Pulse Therapy

测定了20例持续不卧床腹膜透析（CAPD）患者治疗前、后的血清甲状旁腺素（1～84）的含量，并观察了1，25（OH）2D3大剂量冲击和常规剂量每日口服对CAPD患者血清PTH（1～84）的浓度的影响。结果显示1，25（OH）2D3口服能降低CAPD患者血清PTH（1～84），纠正低钙血症，口服冲击疗法优于常规剂量口服疗法。

Level of PTH(1-84) of 20 patients receiving continuous ambulatory peritoneal dialysis(CAPD) was measured before and after pulse therapy. Influence on PTH(1-84) with oral 1, 25 (OH)2D3 pulse therapy and routine dose 1, 25 (OH)2D3 was observed. The results showed: oral 1, 25(OH)2D3 decreased PTH(1-84) and improved hypocalcemia. Besides, pulse therapy had a better effect.