摘要
评价超细三七粉致畸作用。将健康SD受孕大鼠45只随机分为4组,每组10-12只,于孕第7~16d连续分别经口给予含超细三七粉0%、2.5%、5.0%、10.0%饲料,观察致畸作用。结果表明,超细三七粉在饲料中最高添加量10%(实际摄入量为7.81g/kg.bw.d)时,未发现胚胎毒性和致畸作用。
Total 45 SD rats were divided randomly into 4 groups, and each group was administered orally with the radix notoginseng powder at the dose of 0%, 2.5%, 5.0%, 10.0% for 10 days. The results showed that there were no embryotoxieity and teratogenieity effects when 10% radix notoginseng powder was added.
关键词
超细三七粉
大鼠
致畸性
Radix notoginseng powder
Rat
Teratogenicity