脑卒中后并发抑郁症的临床分析

Clinical analysis of concurrent post stroke depression

目的对脑卒中后并发抑郁症的；临床资料进行分析。方法对128例脑卒中患者，根据汉密尔顿抑郁量表评分，分为伴抑郁脑梗死组（A组）49例，无抑郁对照组（B组）79例，分析脑梗死发生部位与抑郁症、脑卒中抑郁与神经功能缺损程度的关系。结果脑卒中后抑郁的发生率为38．28％（49／128）；左侧半球脑卒中与右侧组比较，差异有统计学意义（P〈0．05）；A组在左侧半球基底结、额颞叶及其他部位上的脑卒中分布，差异有统计学意义（P〈0．05）。神经功能正常与不同程度的神经功能缺损组其抑郁情绪正常、轻度、中度、重度间存在明显的相关性（P〈0．01）。结论脑卒中后抑郁症与脑卒中的部位有关，神经功能缺损程度与抑郁也有相关性。

Objective Analysis of clinical data of concurrent post stroke depression. Methods 128 patients with post stroke, according to Hamilton Depression Rating Scale （HAMD） score, are divided into 2 groups, one with depression, cerebral infarction（ A group ,49 cases）, the other with none- depression （B group ,79 cases ） ; analysis of the relationship between the site of cerebral infarction and depression, poststroke depression and the degree of neurological impairment. Results The incidence of post - stroke depression is 38.28% （49/128） ; comparison between the left hemisphere stroke and the right group, the difference is statistically significant （ P 〈 0.05 ） ; the regions of disease of group A pa- tients are located in basal node of the left hemisphere,frontal temporal lobe and other parts of the brain,the difference is statistically significant （P 〈 0.05 ）. Clear correlation existed between nerve function normalization and varying degrees of neurological impairment groups,the degree is listed as normal, mild, moderate, severe （ P 〈 0.01 ）. Conclusion Post stroke depression and the site of PSD are related, neurological deficits and depression are also relevant.