摘要
创造了两步合成2-芳基苯并呋喃化合物的新方法。即利用水杨醛或取代水杨醛在低价钛作用下进行交叉McMurry偶联反应,并对交叉偶联产物-邻乙烯基苯酚进行氧化环化获得对应苯并呋喃化合物。此法为脱甲氧基野茉莉醇、野茉莉醇等天然产物的全合成提供了简便有效的方法。
A novel two-steps synthesis of 2-arylbenzofurans has been developed.Firstly,via selective cross McMurry coupling reaction with salicylaldehyde or substituted salicylaldehyde,ortho-vinylphenols was prepared in the presence of low value titanium ion,and then converted into 2-arylbenzofurans by xidative cyclization reaction.It is shown that this method would be efficiently suitable to synthesis demethoxyegonol products.
出处
《化学试剂》
CAS
CSCD
北大核心
2010年第2期177-180,共4页
Chemical Reagents
基金
新疆师范大学优秀青年教师科研启动基金(XJNU0731)
