不同剂量丙种球蛋白治疗川崎病疗效分析

Clinical analysis on the treatment of Kawasaki Disease with different pose of intravenous inmunoglobulin infusion.

目的探讨不同剂量丙种球蛋白静脉注射对川崎病的疗效。方法回顾性分析30例川崎病患儿应用不同剂量丙种球蛋白的疗效。结果在发热消退、结膜充血恢复和血沉恢复方面，1d疗法优于5d疗法，差异有统计学意义（P〈0．05）。在颈淋巴结消退、C反应蛋白、心电图的恢复方面，两者比较差异无统计学意义（P〉0．05）。在预防冠状动脉扩张方面，1d疗法疗效显著，与5d疗法比较差异有统计学意义（P〈0．01）。结论早期应用大剂量丙种球蛋白对川崎病患儿临床疗效显著。

Objective To study the effect of the treatment of KD with different pose of in intravenous inmunoglobulin infusion. Methods To anlysis the treated effect of 30 cases with KD with different pose of in intravenous inmunoglobulin infusion. Results In treatment of fever, conjunctive congest and recover in erythrocyte sedinentation, one - day treatment had better curative effect with significantly difference （ P 〈 0. 05 ） , compared with five - day. In the extinction of lymphlonodi cervieales, C - RP and electrocardiogram, there was no difference between the two modalities （P 〉 0.05 ）. In the prevention of coronary arterydilate （CAD） , one - day treatment had better effects significantly （ P 〈 0.01 ）, compared with five - day. Conclusion There was better curative effect to cases with KD with large pose of intrarenous inmunoglobulin infusion in advance.