早产母乳免疫物质和蛋白测定

The Determination of Immuual Substances and Proteins in Milk of Premature Delivery Mother

目的：为提高早产儿抗病能力，降低发病率，早产母乳（初乳）的免疫球蛋白及补体含量水平应予以研究。方法：应用单向扩散法和双缩脲法分别测定30例早产产妇初乳和30例足月产产妇初乳中免疫球蛋白sIgA、IgA、IgG、IgM、补体C3、C4和蛋白含量。结果：1．早产初乳较足月产初乳含有更丰富的免疫球蛋白及补体，有利于提高早产儿的抗病能力；2．早产初乳较足月产初乳含更丰富的蛋白，以满足早产儿生长发育需要；3．早产组随孕周增长，免疫球蛋白及补体量却下降。结论：早产儿死亡率高，早产儿合理喂养至关重要。早产初乳较足月产初乳合更多蛋白，应哺自身母乳，以满足新生儿生理病理需要；母乳库应将收集到的足月产与早产母乳分别贮存，以适应各种不同情况的需要。

OBJECTIVE To improve the disease prevention of premature delivery the content of immunoprotein and addiment in colostrum should be detected. METHODS The level of immuno-protein (sIgA, IgA,IgG and IgM), addiment (C3 and C4) and protein in colostrum for 60 mothers are tested by single dimensionaldoffusion and binret test. RESULTS (1) The content immuno-protein, addiment and protein in colostrure of premature delivery is more than that of term birth. (2) With the increasing of pregnant weeks, the content of immuno-protein and addiment is decreased in premature delivery. CONCLUSION The premature fetus is fed withthe mother's colostrum can meet the needs. The breast milk of premature delivery and term birth should bestored separately in order to be used in different situations.