宫颈癌根治术中卵巢移位36例临床分析

Clinical analysis of 36 cases with ovary transposition at the time of radical hysterectomy of cervical carcinoma

目的探讨年轻宫颈癌患者根治术中行卵巢移位术后移位卵巢的功能状况。方法36例45岁以下的宫颈癌患者在根治性手术的同时实施了卵巢移位术，其中术后辅助放疗21例。通过血清性激素水平的测定及随访性生活状况等评估术后卵巢功能。结果36例卵巢移位患者术前术后血清性激素水平无统计学差异（P〉0．05）。卵巢移位术后放疗组雌、孕激素水平较未放疗组低（P〈0．05）。随访中，无1例因卵巢移位复发。结论卵巢移位术是保留年轻宫颈癌患者卵巢功能安全有效的方法，放射治疗对移位卵巢的功能有不良影响。

Objective To investigate the function of transposited ovaries following radical hysterectomy in young patients with cervical carcinoma. Methods 36 patients with cervical carcinoma under the age of 45 years received ovary transposition at the time of radical hysterectomy. 21 patients received postoperation radiotherapy. Ovary function was evaluated by assaying the levels of serum sex hormone and following - up the sexual situation. Results The levels of serum sex hormone had no difference before and after operatiou（P 〉0. 05 ）. The levels of estradiol and progesterone in postoperation radiotherapy group were lower than that in the no radiotherapy group（ P 〈0. 05 ）. No ovary metastasis developed during the following - up period. Conclusion Ovary transposition is a safe and effective method of preserving ovarian function in young patients with cervical carcinoma. Radiotherapy has adverse effect for transposed ovary function.