1Azucena E, Mobashery S. Aminoglycoside- modifying enzynms:mechanisms of catalytic processes and inhibition [J]. Drug Resist Updat ,2001,4(2) : 106.
2Ruiz J, Sierra J M, De Anta M T, et al. Characterization of sparlloxacin- resistant mutants of Staphylococcus aareus obtained in vitro [J]. Ira J Antimicrob Agents ,2001,18(2) : 107.
3Akasaka T,Tanaka M,Yamaguchi A, et al.Type H topoisomerase mutations in fluoroquinolone - resistant clinical strains of Pseudomonas aeruginosa isolated in 1998 and 1999: role of target enzyme in mechanism of fluoroquinolone resistance [J]. Antimicrob Agents Chemother ,2001, 4 5 ( 8 ) :2263.
4Ho P L, Yam W C,Que T L, et al.Target site modifications and eftlux phenotype in clinical isolates of Streptocotrus pneumoniae from Hong Kong with reduced susceptibility to fluoroqulndones [ J]. J Chernother, 2001,47(5) :655.
5Culebras E, Marfinez J L. Aminoglycoside resistance mediated by the bifunctional enzyme 6' - N - aminoglycoside acetyltransferase - 2" - 0 - aminoglycoside phosphotransferase [ J ]. Front Biosci, 1999, 4:1.
6Stapleton P D, Taylor P W. Methicillin resistance in Staphylococcus aztreus: mechanisms and modulation [ J ]. Sci Prog, 2002, 85 ( Pt 1):57.
7Pechere J C. Macrolide resistance mechanisms in Gram- positive cocci [J]. Int J Antimicrob Agents. 2001,18(Suppl 1) : $25.
8Adamson I,Edlund C, Nord C E. Microbial ecology and treatment of Helicobacter pylori infections [J]. J Chemother,2000,12(1) :5.
9Widdowson C A, Klugman K P. Molecular mechanisms of resistance to commonly used non - betalactam drugs in Streptococcus pneumoniae[J]. Semin Respir Infect, 1999, 14(3) :255.
10Hiramatsu K. Vancomycin - resistant Staphylococcus aureus : a new model of antibiotic resistance [ J]. Lancet Infect Dis, 2001, 1 (3) : 147.