桥小脑角肿瘤患者的听觉脑干诱发电位及短潜时体感诱发电位研究

Study of Brainstem Auditory Evoked Potential and Short Latency Somatosensory Evoked Potential in Patients with Cerebrallopontine Angle Tumor

目的研究桥小脑角肿瘤(Cerebrallopontine angle tumor,CPAT)患者的听觉脑干诱发电位(Brain stenl auditory evoked potential,BAEP)及短潜时体感诱发电位(Short latency somatosensory evoked potential,SSEP) 方法用多功能生理反应记录仪对30例CPAT患者同时进行了BAEP和SSEP的测定。结果单侧CPAT患者,小型肿瘤组病侧BAEP异常、健侧BAEP及SSEP正常;中型肿瘤组病侧BAEP异常、健侧BAEP正常,部分患者可伴有病侧SSEP的NT+W值及N_(20)-N_9-W值延长;大型肿瘤组病侧BAEP异常、部分患者伴有健侧BAEPⅢ～ⅴIPL延长及健侧或病侧SSEP的NT+W值、N_(20)-N_9-W值延长。结论提出CPAT患者电生理诊断标准:轻型,仅有病侧BAEP异常;中型,病侧BAEP异常伴病侧SSEP异常;重型,病侧BAEP及SSEP异常伴健侧BAEPⅢ～ⅤIPL延长或健侧SSEP的NT+W值及N_(20)-N_9-W值延长。此标准更能确切反应肿瘤大小及其对脑干功能的影响。BAEP双侧Ⅰ～ⅢIPL延长或各波消失是双侧CPAT患者的特征性表现。

Objective Brainstem auditory evoked potential(BAEP) and short latency somatosensory evoked potemial(SSEP) in 30 cases with eerebrallopontine angle tumor(CPAT) were studied. Methods Muliple function recorder of physiological response was adopted in 30 cases of CPAT for determination of BAEP and SSEP. Results In small unilateral tumor, BAEP on focal side was abnormal while normal on non-focal side. BAEP on focal side in moderate tumor was abnormal while normal but SSEP on non-focal side in some cases was abnormal. The patients with large tumor had abnormalily of BAEP and SSEP on focal side, and prolongation of Ⅲ～Ⅴ IPL of BAEP on non-focal side. Conclusion Based on this study, standard of electrophysiological diagnosis was set up: abnormal BAEP only existed on focal side as mild abnormalily, both abnormal BAEP and SSEP existed on focal side as moderate abnormality, both ahnormal BAEP and SSEP esisted on focal side, with prolongation of Ⅲ～Ⅴ IPL of BAEP and NT +W, N_(20)-N_9-W of SSEP on non-focal side as severity. The standard more accurately reflceets size of tumor and its effect on brain stem. Ⅰ～Ⅲ IPL prolongation of BAEP or disappearance on both sides are characteristic features of CPAT.