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神经精神性狼疮的诊断与治疗进展 被引量:6

New Development on the Diagnosis and Treatment of NPSLE
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摘要 神经精神性狼疮诊断和治疗尚无统一的标准,容易被漏诊、误诊。近来关于脑脊液和血清中抗神经元抗体、抗核糖体P蛋白抗体等抗体检测,可溶性fractalkine检测,CT、磁共振成像、单光子发射计算机断层显像、正电子发射成像、磁化传递成像、磁共振波谱分析、磁共振弥散张量成像检查以及治疗特别是利用生物制剂治疗,例如利妥昔单抗、依帕珠单抗、贝利单抗的研究与应用有了一些新的内容,因此对诊断和治疗的进展作了综述。 There are no uniform criteria for the diagnosis and treatment of neuropsychatric lupus erythymatosus(NPSLE).NPSLE might be easily missed and misdiagnosed.New researches on the antibodies such as anti-neuronal antibodies etc,imaging diagnosis such as CT,MRI etc,treatment especially the application of biological agents have been done in resent years,which are helpful for the diagnosis and treatment of NPSLE,therefore they are reviewed in this paper.
作者 阎萍 周晓鸿
出处 《医学综述》 2010年第5期722-724,共3页 Medical Recapitulate
关键词 系统性红斑狼疮 神经精神性狼疮 诊断 治疗 Systemic lupus erythematosus Neuropsychiatric lupus erythymatosus Diagnosis Therapy
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参考文献21

  • 1Matus S, Burgos PV, Bravo-Zehnder M, et al. Antiribosomal-P autoantibodies from psychiatric lupus target a novel neuronal surface protein causing calcium influx and apoptosis [ J ]. J Exp Med, 2007,204( 13 ) :3221-3234.
  • 2Kiss E,Shoenfeld Y. Are anti-ribosomal P protein antibodies relevant in systemic lupus erythematosus[ J ]. Clin Rev Allergy Immunol,2007,32( 1 ) :37-46.
  • 3Tin SK,Xu Q,Thumboo J,et al. Novel brain reactive autoantibodies: prevalence in systemic lupus erythematosus and association with psychoses and seizures[ J]. Neuroimmunol,2005,169 (1/2): 153-160.
  • 4朱孟铸,王吉波.神经精神狼疮的自身抗体及影像学检查[J].齐鲁医学杂志,2009,24(4):373-376. 被引量:1
  • 5Castellino G,Govoni M, Giacuzzo S,et al. Optimizing clinical monitoring of central nervous system involvement in SLE[ J]. Autoimmun Rev,2008,7(4) :297-304.
  • 6Castellino G, Padovan M, Bortoluzzi A, et al. Single photon emission computed tomography and magnetic resonance imaging evaluation in SLE patients with and without neuropsychiatric involvement [ J ]. Rheumatology ( Oxford ) ,2008,47 ( 3 ) :319-323.
  • 7Emmer B J, Steens SC, Steup-Beekman GM, et al. Detection of change in CNS involvement in neuropsychiatric SLE:a magnetization transfer study [ J ]. Magn Reson Imaging, 2006, 24 ( 4 ) : 812-816.
  • 8Welsh RC, Rahbar H, Foerster B,et al. Brain diffusivity in patients with neuropsychiatric systemic lupus erythematosus with new acute neurological symptoms[ J ]. Magn Reson Imaging, 2007,26 ( 3 ): 541-551.
  • 9Fitzqibbon BM, Fairhall SL, Kirki IJ, et al. Functional MRI in NPSLE patients reveals increased parietal and frontal brain activation during a working memory task compared with controls [ J ]. Rheumatology ( Oxford ) ,2008,47 ( 1 ) :50-53.
  • 10Jose J, Paulose BK, Vasuki Z,et al. Mycophenolate mofetil in neuropsychiatric systemic lupus erythematosus [ J ]. Indian J Med Sci, 2005,59(8) :353-6.

二级参考文献37

  • 1张奉春,董怡,赵玉华,林禾,姜泉,赵杰.系统性红斑狼疮中枢神经系统病变的诊断及治疗[J].北京医学,1994,16(5):277-280. 被引量:23
  • 2潘琳,王吉波,谢荣爱.系统性红斑狼疮的辅助检查[J].青岛大学医学院学报,2007,43(2):187-188. 被引量:7
  • 3OMDAL R, BROKSTAD K, WATERLOO K, et al. Neuro psychiatric disturbances in SLE are associated with Abs against NMDA receptors[J]. Eur J Neurol, 2005,12:392-398.
  • 4HUSEBYE E S, STHOEGER Z M, DAYAN M, et al. Autoantibodies to a NR2A peptide of the glutamate/NMDA re ceptor in sera of patients with systemic lupus erythematosus [J]. Ann Rheum Dis, 2005,64(8) :1210-1213.
  • 5WEINER S M, KLEIN R, BERG P A. A longitudinal study of autoAbs against central nervous system tissue and gangliosides in connective tissue diseases[J]. Rheurnatol Int, 2000,19 (3) : 83-88.
  • 6WATANABE H, SEINO T, SATO Y. Antibodies to triose-phosphate isomerase in patients with neuropsychiatrie lupus [J]. Biochim Biophys Res Communications, 2004, 321 (4) : 949- 953.
  • 7SASAJIMA T, WATANABE H, SATO S, et al. Anti-triose- phosphate isomerase antibodies in cerebrospinal fluid are associated with neuropsychiatric lupus [J]. J Neuroimmunol, 2006,181 (1-2) : 150-156.
  • 8JENNINGS J E, SUNDGREN P C, ATTWOOD J, et al. Value of MRI of the brain in patients with systemic lupus cry thematosus and neurologic disturbance[J]. Neuroradiology, 2004,46(1) :15- 21.
  • 9APPENZELLER S, PIKE G B, CLARKE A E. Magnetic resonance imaging in the evaluation of central nervous system manifestations in systemic lupus erythematosus[J]. Clinic Rev Allerg Immunol, 2008,34:361-366.
  • 10CASTELLINO G, GOVONI M, GIACUZZO S, et al. Optimizing clinical monitoring of central nervous system involve ment in SLE[J]. Autoimmun Rev, 2008,7(4) :297-304.

共引文献32

同被引文献32

  • 1沈思钰,赵智明,修春英,商玮,董晓蕾,赵凌杰,蔡辉.神经精神狼疮3例报告并文献复习[J].中国实用内科杂志,2005,25(12):1140-1141. 被引量:7
  • 2陆再英,钟南山.内科学[M].第7版.北京:人民卫生出版社.2008:251.
  • 3Sherling G, West MD. Neuropsychiatric lupus [ J ]. Rheum Dis Clin North Am, 1994, 2 : 129.
  • 4Zhou HQ, Zhang FC, Tian XP, et al. Clinical features and outcome of neuropsychiatric lupus in Chinese: analysis of 240 hospitalized patients[J]. Lupus, 2008, 17 : 93 - 99.
  • 5ACR AD HOC. Committee on Neuropsychiatric Lupus Nomenclature. The American College of Rheumatology no menclature and casedefinitions for neuropsychiatric lupus syndromes[J]. Arthritis Rheum, 1999, 42:599 - 608.
  • 6Fragoeo - Loyo H, Richaud - Patin Y, Orozco - Narvaez A, et al. lnterleukin, 6 and chemokines in the neuropsychiatric manifestations of systemic lupus erythernatosus[ J ]. Arthritis Rheum, 2007,56:1 242- 1 250.
  • 7Borchers AT, Aoki CA, Naguwa SM, et al. Neuropsychiatric features of systemic lupus erythematosus[ J ]. Autoimmun Reu, 2005,4(6):329- 344.
  • 8徐建银,刘泽有,郑献召.鞘内注射联合甲基泼尼松龙冲击治疗神经精神性狼疮72例观察[J].中国实用神经疾病杂志,2008,11(9):114-115. 被引量:1
  • 9王晓东,高文风,王炎强,王英亮,张明,刘润荣,孙希志.神经精神性狼疮的脑脊液分析[J].潍坊医学院学报,2008,30(3):217-218. 被引量:1
  • 10梁有禄,陈琪,黄永杰,裴锐昌,宋国武.神经精神性系统性红斑狼疮的MRI表现与临床分析[J].贵阳医学院学报,2009,34(1):93-94. 被引量:2

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