术前肠内营养对食管癌病人术后营养状况的影响分析

Influence of preoperative enteral nutrition on nutritional status in postoperative patients with esophageal carcinoma

目的研究术前肠内营养支持对食管癌病人术后营养状况的影响。方法对2008年1月至2008年12月河北医科大学附属唐山工人医院40例食管癌的临床资料进行分析。将40例食管癌病人随机分为两组,对照组20例,行术后早期肠内营养(EEN);治疗组20例,在EEN基础上术前口服能全素,肠内营养支持。所有病人均于术前1日及术后第8日测量体重,抽取静脉血测定血红蛋白及血清白蛋白含量,并于第8日留24h尿测尿素氮,计算氮平衡。结果治疗组与对照组比较,术后第8日体重变化差异无统计学意义(P>0.05);血红蛋白、血清白蛋白含量及氮平衡比较,治疗组明显优于对照组,差异有统计学意义(P<0.05)。结论术前肠内营养支持能明显改善食管癌病人术后的营养状况。

Objective To investigate the influence of preoperative enteral nutrition on nutritional status in postoperative patients with esophageal carcinoma. Methods The clinical data of 40 patients with esophageal carcinoma admitted between January 2008 and December 2008 at Tangshan Workers Hospital of Hebei Medical University were analyzed. All the patients were randomly allocated into two groups. Each group included 20 patients. In the control group, patients received only early enteral nutrition （EEN） postoperatively. In the treatment group, patients received not only preoperative EEN but also Nutrison by mouth preoperatively for enteral nutrition support. The body weight, hemoglobin and serum albumin were measured on the day before operation and the eighth day after operation. On the eighth day, 24h urine sample was collected and urea nitrogen were measured to calculate the balance of nitrogen. Results There was no significant deviation between the two groups （P〉0.05）. The treatment group showed significantly increased in the hemoglobin, serum albumin, nitrogen balance compared with the control group （P〈0.05）. Conclusion Preoperative enteral nutrition can improve the nutrition status of postoperative patients with esophageal carcinoma.