超声评价颈动脉内膜-中层厚度及斑块与冠心病的相关性

Correlation of Carotid Artery Intima-Media Thickness and Plaque with Coronary Heart Disease:Evaluation by Color Doppler Ultrasound

目的通过超声检测颈动脉内膜-中层厚度(IMT)及粥样硬化斑块,探讨颈动脉硬化与冠心病(CHD)的相关性。方法应用彩色多普勒超声测量经冠状动脉造影(CAG)确诊的58例CHD患者和37例非CHD患者颈动脉IMT及有无斑块形成,比较两组间颈动脉IMT、斑块指数及颈动脉斑块检出率。结果CHD组颈动脉IMT、斑块指数及斑块检出率显著高于非CHD组(P<0.05),颈动脉IMT对CHD诊断有较高的敏感性及特异性。结论超声检测颈动脉IMT可早期发现冠状动脉粥样硬化,可作为监测冠状动脉疾病发生、发展及治疗效果的一项有临床意义的指标。

Objective To investigate the correlation between cervical atherosclerosis and coronary heart disease（CHD） by detecting intima-media thickness（IMT） and plaque in carotid artery. Methods The carotid artery IMT and plaque were measured by color doppler ultrasound in 58 cases of CHD（CHD group） and 37cases of non-CHD（non-CHD group） conformed by coronary angiography. The carotid artery IMT,plaque index and carotid artery plaque detection rate were compared between the two groups. Results The carotid artery IMT and plaque index of the CHD group were significantly higher than those of the non-CHD group（P〈0.05）. The detection rate of carotid plaque of the CHD group was significantly higher than that of the non-CHD group. The carotid artery IMT had higher sensitivity and specificity to CHD diagnosis. Conclusion Carotid artery IMT may reflect an early coronary atherosclerosis,which can serve as a clinical indicator for monitoring the occurrence,development and treatment of coronary artery disease.