血红素蛋白模拟(Ⅱ)——尾式噻吩基金属卟啉的合成与表征

Simulation of hemoproteins (Ⅱ)??synthesis and characterization of thiophene tailed metalloporphyrins

探讨了一种新型尾式卟啉——５－邻［４－（２－噻吩甲氧基）丁氧基］苯基－１０，１５，２０－三苯基卟吩（简称ｏ－ＴｈｉｏＴＰＰ）的合成方法。以ｏ－ＴｈｉｏＴＰＰ为配体合成了金属铁卟啉ｏ－ＴｈｉｏＴＰＰＦｅ（Ⅲ）Ｃｌ和金属锰卟啉ｏ－ＴｈｉｏＴＰＰＭｎ（Ⅲ）Ｃｌ。通过元素分析、质谱、紫外可见光谱、红外光谱、核磁共振氢谱和碳谱顺磁共振波谱等手段对上述化合物进行了表征，结果表明，三价金属卟啉处在高自旋状态。

A new tailed porphyrin with a thiophene covalently attached as an axial ligand,5 o [4 (2 thiophenemethanoxy) butanoxyl]phenyl 10,15,20 triphenyl porphine ( o ThioTPP),its ferric coordination compound ( o ThioTPPFe(Ⅲ)Cl) and manganese coordination compound ( o ThioTPPMn(Ⅲ)Cl) have been synthesized These compounds were characterized by elemental analysis,MS,UV Vis,IR, 1HNMR, 13 CNMR and EPR spectra The results show that the metal ions of the metalloporphyrins are in high spin state and the terminal thiophene does not coordinate with the metal ions