期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

多b值弥散加权成像的综合应用研究 被引量：7

A Comprehensive Application Research of Multi b Value Diffusion Weighted Imaging
原文传递
导出
摘要 该研究介绍了一种分析人大脑水分子弥散信息的新方法。该方法通过综合利用多b值的弥散加权成像信息,使用新的算法,计算出一个新的弥散参数(Rd),并重建出该参数的图像。在对25名正常成人脑组织的定量研究结果表明,相比于表观弥散系数(ADC),该方法能明显提高弥散图像的信噪比,有效区分大脑不同组织结构,提高了对水分子弥散运动的敏感性。 This research introduces a new method to analyze the diffusion information of human brain.By use of the multi b value diffusion data and a new algorithm,a new diffusion parameter（Rd） was computed,and a new image was reconstructed.Through quantitative research on the brains of 25 normal adults,the new method can improve the signal-to-noise ratio（SNR） apparently and distinguish the different brain tissues effectively,compared to the apparent diffusion coefficient.The new method can improve the sensitivity to diffusion.
作者 雷正勇 朱莉 汤伟军 冯晓源
机构地区 复旦大学附属华山医院放射科 复旦大学上海医学院医学信息学专业
出处 《生物医学工程学杂志》 EI CAS CSCD 北大核心 2010年第1期37-41,共5页 Journal of Biomedical Engineering
基金 卫生部部属(管)医院临床学科重点项目资助
关键词 弥散加权成像 B值 脑 Diffusion-weighted Imaging（DWI） b-value Brain
分类号 R445.2 [医药卫生—影像医学与核医学]
  • 相关文献

参考文献10

  • 1FISCHER M, BOCKHORST K, MATHIAS H B, et al. Imaging of the apparent diffusion coefficient for the evaluation of cerebral metabolic recovery after cardiac arrest[J]. Magnetic Resonance Imaging, 1995,13 : 781-790.
  • 2杨正汉,冯逢,王霄英,等.磁共振成像技术指南[M].北京:人民军医出版社,2007:85-88.
  • 3MARK C, DELANO, CAO Y. High b-value diffusion imaging[J]. Neuroimaging Clinics of North America, 2002,12:21-34.
  • 4DANIEL A, HAMSTRA, REHEMTULLA A, et al. Diffusion magnetic resonance imaging, A biomarker for treatment response in oneology[J]. Journal of Clinical Oncology, 2007, 25:4104-4109.
  • 5SORENSEN A G. Magnetic resonance as a cancer imaging biomarker[J]. J Clin Oncol, 2006, 24 :3274-3281.
  • 6MULKERN R V, GUDBJARTSSON H, WESTIN C F, et al. Multi-component apparent diffusion coeddicients in human brain[J].NMR Biomed, 1999, 12:51-62.
  • 7NIENDORF T, DIJKHUIZEN R M, NORRIS D G, et al. Biexponential diffusion attenuation in various states of brain tissue: Implications for diffusion-welghted imaging [J].MRM, 1996,36:847-847.
  • 8MARDOR Y, ROTH Y, AHARON O, et al. Pretreatment prediction of brain tumors' response to radiation therapy using high b-Value dlffuslon-weighted MRI [J]. Neoplasia, 2004, 6:136-142.
  • 9ROTH Y, THOMAS T, KOSTENICH G, et al. High-b- Value diffusion-weighted MR imaging for pretreatment prediction and early monitoring of tumor response to therapy in mice[J]. Radiology, 2004, 232: 685-692.
  • 10高嵩,包尚联.扩散时间及扩散梯度磁场对水分子表观扩散系数的影响[J].生物医学工程学杂志,2008,25(3):542-546. 被引量：7

二级参考文献8

  • 1[1]Stejskal EO,Tanner JE.Spin diffusion measurements:spin echoes in the presence of a time-dependent field gradient.Journal of Chemical Physics,1965; 42(1):288
  • 2[2]DeLano MC,Cooper TG,Siebert JE,et al.High-b-value diffusion-weighted MR imaging of adult brain:image contrast and apparent diffusion coefficient map features,AJNR,2000;21(10):1830
  • 3[3]Yoshiura T,Wu O,Zaheer A,et al.Highly diffusion-sensitized MRI of brain:dissociation of gray and white matter.Magn Reson Med,2001;45(5):734
  • 4[4]Gates L,Cameron I.Time dependence of water diffusion in human white matter.In:Proc 3rd Annual Meeting ISMRM,Nice,France,1995;355-356
  • 5[5]Horsfield MA,Barker GJ,McDonald WI.Self-diffusion in CNS tissue by volume-selective proton NMR.Magn Reson Med,1994;31(6):637
  • 6[6]Le Bihan D,Turner R,Douek P.Is water diffusion restricted in human white matter? An echo planar NMR imaging study.NeuroReport,1993;4(7):887
  • 7[7]Clark CA,Hedehus M,Moseley ME.Diffusion time dependence of the apparent diffusion tensor in healthy human brain and white matter disease.Magn Reson Med,2001;45(6):1126
  • 8[10]Basser PJ,Pierpaoli C.A simplified method to measure the diffusion tensor from seven MR images.Magn Reson Med,1998;39(6):928

共引文献198

同被引文献84

  • 1陈军,夏军,周义成,夏黎明,朱文珍,邹明丽,冯定义,王承缘.星形细胞瘤磁共振弥散加权成像与肿瘤细胞密度的相关性研究[J].中华肿瘤杂志,2005,27(5):309-311. 被引量：20
  • 2郭晓强.水甘油通道蛋白与甘油运输研究进展[J].军事医学科学院院刊,2007,31(5):487-489. 被引量：5
  • 3Koh DM, Collins DJ. Diffusion-weighted MRI in the body: appli- cations and challenges in oncology [J:. AJR Am J Roentgenol, 2007,188(6) : 1622-1635.
  • 4Padhani AR,Liu G,Koh DM,et ah Diffusion-weighted magnetic resonance imaging as a cancer biomarker: consensus and recom- mendations[J]. Neoplasia, 2009,11 (2) : 102-125.
  • 5Razek AA, Megahed AS, Denewer A, et al. Role of diffusion- weighted magnetic resonance imaging in differentiation between the viable and necrotic parts of head and neck tumors [J]. Acta Radiol, 2008,49 ( 3 ) : 364-370.
  • 6Galban S, Brisset JC, Rehemtulla A,et al. Diffusion-weighted MRI for assessment of early cancer treatment response [J]. Curt Pharm Biotechnol, 2010,11 (6) : 701-708.
  • 7Thoeny HC,Ross BD. Predicting and monitoring cancer treatmentresponse with diffusion-weighted MRI [J]. J Magn Reson Imag- ing,2010,32(1) :2-16.
  • 8Abdel Razek AA,Kandeel AY,Soliman N,et al. Role of diffu- sion-weighted echo-planar MR imaging in differentiation of resid- ual or recurrent head and neck tumors and posttreatment changes [J]. AJNR Am J Neuroradiol, 2007,28(6) : 1146-1152.
  • 9Kim S,Loevner L,Quon H,et al. Diffusion-weighted magnetic resonance imaging for predicting and detecting early response to chemoradiation therapy of squamous cell carcinomas of the head and neck[J]. Clin Cancer Res,2009,15(3) :986-994.
  • 10Khoo MM,Tyler PA, Saifuddin A,et al. Diffusion-weighted imag- ing (DWI) in musculoskeletal MRI: a critical review[J]. Skele- tal Radiol, 2011,40(6) :665-681.

引证文献7

二级引证文献34

生物医学工程学杂志
2010年 第1期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部