摘要
以对硝基氯苯为原料，经四步合成制得中间体２，６－二氯苯并口恶唑；以对苯二酚和２－氯丙酸为原料，经一步合成了另一中间体２－（４－羟基苯氧基）丙酸乙酯，两个中间体在二甲亚砜溶剂中，碳酸钠存在下缩合得到标题化合物，全程收率为４３％。
Two intermediats,2,6 dichlorobenzoxazole and ethyl 2 (4 hydroxyphenoxy)propionate,were prepared from cheap material p nitrochlorobenzone in four steps and from p dihydroxybenzene and 2 chloropropionate in one step,respectively.Then the title compound,ethyl 2[4 (6 chloro 2 benzoxazoloxy)phenoxy]propionate,was synthesized from the intermediats in the presence of sodium carbonate in the solvent of methyl sulfoxide.Total yield is 43%.
出处
《合成化学》
CAS
CSCD
1998年第3期328-331,共4页
Chinese Journal of Synthetic Chemistry
关键词
降草剂
威霸
丙酸乙酯
苯氧基
苯并恶唑氧基
Heterocyclic compound, Herbicide, Synthesis, Whip,2,6 dichlorobenzoxazole,Ethyl 2 (4 hydroxyphenoxy)propionate .
