糖尿病患者抗Pra抗体致迟发性溶血性输血反应及分析

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摘要蛋白酶敏感的Pr抗原最早被Marsh和Jenkins命名为Sp1，被Roelcke命名为HD。它们通常被冷抗体性质的IgM型人源单克隆自身抗体检测到，这些自身抗体或来自冷凝集素疾病或是由感染引发的，只有在罕见的情况下是与自身免疫性溶血性贫血相关。

作者洪慧东於王骐潘峰王金龙高莉王家芷陈兆军

机构地区杭州师范大学附属医院检验科

出处《中华检验医学杂志》 CAS CSCD 北大核心 2010年第2期183-184,共2页 Chinese Journal of Laboratory Medicine

关键词迟发性溶血性输血反应抗体检测 PRA 糖尿病患者自身免疫性 IGM型抗体性质

参考文献8

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3Marsh WL, Jenkins WJ. Anti-Spl : the recognition of a new cold auto-antibody. Vox Sang, 1968, 15: 177-186.
4Roelcke D. A new serological specificity in cold antibodies of high titre: anti-HD. Vox Sang, 1969, 16: 76-79.
5Roelcke D, Kreft H. Characterization of various anti-Pr cold agglutinins. Transfusion, 1984, 24 : 210-213.
6Garratty G, Arndt P, Domen R, et al. Severe autoimmune hemolytic anemia associated with IgM warm autoantibodies directed against determinants on or associated with glycophorin A. Vox Sang, 1997, 72: 124-130.
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8Konig AL, Schabel A, Sugg U, et al. Autoimmune hemolytic anemia caused by IgG Lambda-monotypic cold agglutinins of anti- Pr specificity after rubella infection. Transfusion,2001,41:488- 492.

中华检验医学杂志

2010年第2期

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