利凡诺分子模板聚合物的吸附与识别特性研究

Studies on Character of Adsorption and Recognition of Etharidine Template Polymer

以利凡诺药物为模板分子，α－甲基丙烯酸为功能基单体，乙二醇二甲基丙烯酸酯为交联剂，选用分子模板技术，合成了一种新的具有类似于酶或药物受体结合部位为结构特征的分子模板聚合物．研究了它对利凡诺和其它底物的吸附特性和选择性识别能力．结果表明，与组成相同的非模板聚合物相比，利凡诺分子模板聚合物有较大的吸附性能和高度的选择性及识别能力．

By using etharidine as the template molecules, methacrylic acid as the functional monomer and ethylene glycol dimethacrylate as the crosslinking monomer, a kind of new molecular template polymer which had enzyme or recepter analogous binding sites and could highly specifically adsorb etharidine was prepared by molecular template technology. Its adsorption property and selective recognition for etharidine and other substrates were studied. The results showed etharidine template polymer had higher adsorption character, high selectivity and recognition ability, as compared with non template polymer whose chemical composition was the same as it. And ionic interaction and hydrogen bonds played an important role in the selective adsorption of template polymer.