高同型半胱氨酸水平与脑梗死及颈动脉斑块形成的相关性研究

Study on correlation of high plasma homocysteine with cerebral infarction and the formation of carotid plaque

目的探讨高同型半胱氨酸水平与脑梗死及颈动脉斑块形成的相关性，并加以研究分析。方法选取2007年3月至2008年12月治疗的71例脑梗死患者为研究对象，将其设为观察组，检测观察组颈动脉斑块形成的情况；同时选取同期的50名健康人为对照组，检测两组的高同型半胱氨酸水平进行比较，后进行研究分析，后将伴颈动脉斑块者的高同型半胱氨酸水平与不伴颈动脉斑块的脑梗死患者的高同型半胱氨酸水平。结果经比较发现，观察组的同型半胱氨酸水平同对照组比较，P〈0．01，差异有统计学意义；伴颈动脉斑块者的高同型半胱氨酸水平与不伴颈动脉斑块的脑梗死患者的高同型半胱氨酸水平比较，P〈0．05，差异有统计学意义。结论脑梗死患者的高同型半胱氨酸水平对于其诊断治疗有较高的价值，且其可进一步反应颈动脉斑块形成的情况，因此，其值得临床进一步研究探讨。

Objective To study the correlation of high plasma homocysteine with cerebral infarction and the formation of carotid plaque, and to research and analysis. Methods 71 examples with cerebral infarc- tion patients from March 2007 to December 2008 in my courtyard treatment was observation group and the formation of carotid plaque was tested at the same time ,50 examples normal healthy people were selected as the con- trol group. The high plasma homocysteine level of the two groups were tested and compared. The high plasma homocysteine level of cerebral infarction with and without formation of carotid plaque were compared. Results The high plasma homocysteine level of observation group was compared with that of control group , P 〈 0. 05, the difference had statistical significance. The high plasma homocysteine level of cerebral infarction with formation of carotid plaque were compared with that of cerebral infarction without formation of carotid plaque ,P 〈0. 01 ,the difference had statistical significance. Conclusion The level of cerebral infarction with formation of carotid plaque has high value in the diagnostic value of cerebral infarction, and it can reflect the formation of carotid nlaaue, and is worth further studvinz.