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神经节苷脂治疗新生儿缺氧缺血性脑病23例疗效观察 被引量:4

Clinial observation of Ganglioside treatment for 23 cases patients with meonatal hypoxic-ischemic encephalopatly
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摘要 目的探讨神经节苷脂治疗新生儿缺氧缺血性脑病的疗效。方法对23例缺氧缺血性脑病患儿随机分为两组,在常规三项支持及三项对症的基础上治疗组用GM1治疗,对照组加用胞二磷胆碱治疗,观察患儿意识、原始反射、肌张力的恢复时间及新生儿神经行为评分以观察药物疗效。结果治疗组临床症状及体征的恢复及新生儿神经行为评分均优于对照组。结论神经苷脂治疗缺氧缺血性脑病有明显疗效。 Objective Discussion Ganglioside treatment of neonatal hypoxic-ischemic encephalopathy. Methods 23 cases patients with hypoxic-ischemic encephalopathy were randomly divided into two groups,three in the conventional support and the basis of the three symptomatic treatment group with GM1 treatment,the control group plus citicoline treatment,observation of children with the awareness of,primitive reflexes,muscle tone and the recovery time of neonatal behavioral neurological assessment in order to observe the effects of drugs. Results Treatment of clinical symptoms and signs of recovery and neonatal neurobehavioral score were better than the control group. Conclusion Resin glycoside treatment of nerve hypoxic-ischemic encephalopathy have a significant effect.
作者 仝桃玲
出处 《中国实用医药》 2010年第6期50-52,共3页 China Practical Medicine
关键词 神经节苷脂 新生儿 神经细胞 脑缺氧 脑损伤 Gangliosides Newborn Nerve cells Cerebral anoxia Brain Injury
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