囊泡作为药物载体的研究进展

Progress on Vesicle as Drug Carrier

囊泡有较强的增溶能力,其双层膜具有较好的牢固性和稳定性,作为药物载体给药途径较广,载药稳定性、药物增溶量以及药物生物利用度较高。本文介绍了囊泡作为药物载体的研究现状,包括囊泡形成,膜结构选择和应用,以及囊泡在口服给药、局部给药和体内给药的应用。

With significant solubilization and stronger robustness and stability of bilayer, the vesicle as a drug carrier has a series of advantages such as wide administration routes, high stability of drug-loaded and drug solubilization, improved bioavailability of drug. This paper introduces the research on vesicle as a drug carrier, including the formation of vesicle, selection and application of bilayer membrane, and summarizes the applications of vesicle in oral, local and in vivo administration.