本院2005～2008年抗变态反应药应用分析

Analysis of Application of Antiallergics in Dermatological Hospital of Guangxi between 2005 and 2008

目的了解本院抗变态反应药的应用情况。方法对本院2005～2008年抗变态反应药的销售金额、用药频度（DDDs）及日均用药金额（DDDc）进行回顾性分析。结果抗变态反应药销售金额及消耗DDDs占皮肤病用药比例逐年上升。第三代抗组胺药在本院占主导地位。依巴斯汀片、左西替利嗪及曲尼司特胶囊是本院主要应用品种。结论抗组胺药应该向研制更高的抗过敏、抗炎症性能，更低的镇静作用，无心脏毒性，无药物间相互作用药物方向发展。

Objective To investigate the utilization of antiallergic drugs in dermatological hospital of Guangxi Zhuang Autonomous Region. Methods The antiallergics used in our hospital between 2005 and 2008 were retrospectively analyzed regarding the consumption sum and DDDs and DDDc. Results The percentage of the consumption sum and DDDs of antiallergics in the total of dermatologic drugs showed a year-on-year increasing tendency. The third-generation antihistamine was a dominant role in our hospital. Ebastine tablets and Levocetirizine and Tranilast capsules were main kinds. Conclusion Antihistamines should be developed into the medicines which have the better property of antiallergic, antiinflammatory and smaller sedation effect, and without cardio toxicity and interaction between medicines.