高敏C-反应蛋白与老年神经系统疾病

High sensitive C-reactive protein and senile nervous system diseases

高敏C-反应蛋白(hs-CRP)作为一项重要的炎性标志物,参与了动脉粥样硬化、脑血管疾病以及认知功能损害等老年神经系统疾病的发生发展。血清hs-CRP浓度与老年神经系统疾病的发病,病变程度及临床预后密切相关,并且对老年神经系统疾病的预防、治疗、预后判断有重要指导意义。

As a marker of inflammation, high-sensitivity C-reactive protein （hs-CRP） reflects the level of inflammatoin in atherosclerosis, cerebrovascular disease and cognitive impairment. Serum hs-CRP concentrations are associated with increased risk and severity of athero- sclerosis, cerebrovascular disease and cognitive impairment, as well as prognosis of senile nervous system diseases. Serum hs-CRP can be used as the marker for risk assessment in primary and secondary prevention of cerebrovascular disease and be of prognostic value.