3,4-二苯基氧化呋咱的高效合成

Synthesis of 3,4-Diphenylfuroxan with High Efficiency

以苯偶酰为起始原料,通过羟胺加成、邻二肟分子内氧化关环合成了3,4-二苯基氧化呋咱。用红外、核磁氢谱、碳谱及元素分析对其结构进行了表征;研究了氧化剂种类、用量、质量分数及反应温度对成环效率的影响。在次氯酸钠水溶液(次氯酸的质量分数为7.39%)为氧化剂,次氯酸与二苯基乙二肟的摩尔比为3∶1,反应温度80℃,常压,反应时间1.5 h条件下,3,4-二苯基氧化呋咱收率达92.8%。

3,4-Diphenylfuroxan was synthesized using benzil as starting material via hydro amine addition and oxidative cyclization. Its molecular structure has been identified with IR, ^1H NMR, ^13C NMR and elemental analyses. The effect of the category, dosage, mass fraction of oxidants and reaction temperature on the cyclization were investigated. Under the condition of HClO （mass fraction 7.39%） as oxidant, n （HC10） ： n （diphenylglyoxime） = 3, reaction temperature 80℃, atmospheric pressure and reaction time 1. 5h, the yield of 3, 4- diphenylfuroxan was 92.8%.