12例大垂体腺瘤开颅手术治疗的临床分析

Clinic Analysis of 12 Cases Craniotomy on Large Pituitary Adenoma

目的探讨大垂体腺瘤显微开颅手术治疗的适应证和疗效。方法回顾分析12例大垂体腺瘤行开颅显微手术治疗患者的临床资料,并复习相关文献。结果12例均行开颅显微手术治疗,11例全切,1例次全切。术后视力及视野明显改善,8例出现尿崩,药物可控制,3月后症状消失。内分泌激素检查7例恢复正常,无死亡病例。随访3月无肿瘤复发。结论对于大垂体腺瘤手术治疗要进行认真的术前评价,只要适应证选择适当,就能取得最好的手术效果。

Objective To discuss the indication and curative effectiveness of microsurgery craniotomy on large pituitary adenoma.Methods The clinic data of 12 cases of microsurgery craniotomy on large pituitary adenoma were recalled and analyzed,and the related documents were reviewed.Results The 12 cases microsurgery craniotomies have been conducted,in which 6 cases with total resection and 1 case with subtotal resection.After operation,the patients＇ vision and field of view were improved prominently.The diabetes insipidus（DI） occurred to 8 cases,and disappeared after three months by medicine treatment.The hormone examination showed that the endocrine recovered in 7 cases.No death occurred.There was not neoplasm recurrence after follow-up examination.Conclusion The serious appreciation prior to operation shall be done over the microsurgery craniotomy on large pituitary adenoma,and the best surgical result can be achieved by appropriately selecting of adaptation diseases.