L-吡咯烷酮羧酸钠的合成研究

Study on the synthesis of L-pyrrolidone carboxylic sodium

以谷氨酸钠(味精)为原料,采用湿法热解法合成天然保湿因子的主要成分L-吡咯烷酮羧酸钠.正交实验结果表明,在热解反应温度为180℃,反应时间2 h,谷氨酸钠的质量分数60%的条件下,产率可达87.5%.

L-pyrrolidone carboxylic sodium as the composition of the natural moisturizing factor was synthesized by the method of hydrothermal decomposition with sodium glutamate as the raw material. The results of the orthogonal experiments showed that the yield reached 87.5% under the conditions that the temperature of hydrothermal decomposition was 180 ℃, the reaction time for 2h and the mass percent of sodium glutamate about 60 %.