老年慢性肺源性心脏病急性加重期超敏C反应蛋白的临床价值

Clinical Significance of High-sensitivity C-reactive Protein in Senium Patients with Chronic Cor Pulmonale

目的探讨超敏C反应蛋白CRP(hs-CRP)在老年慢性肺源性心脏病(肺心病)急性加重期的临床价值。方法选择2004年9月—2007年10月我院老年肺心病患者急性加重期64例和缓解期60例和健康组65例。检测并比较患者hs-CRP、白细胞(WBC)、血沉(ESR)、痰细菌培养等指标。结果肺心病患者hs-CRP、WBC和ESR均高于健康对照组(P<0.05);肺心病患者急性加重期3个指标均高于缓解期(P<0.05);急性加重期患者hs-CRP阳性率93.8%,远高于其他指标阳性率。结论hs-CRP检测有助于肺心病加重期感染状态的早期诊断,且其反映抗生素的治疗效果,有一定的临床使用价值。

Objective To study clinical significance of high - sensitivity c - reactive protein （ hs - CRP） in senium patients with chronic eor pulmonale. Methods The indexes including hs - CRP, leukocyte （ WBC）, erythrocyte sedimentation rate （ESR） , sputum bacterial culture and X - ray examination of sternite were analysis in 64 cases with chronic cor pulmonale in acute exacerbation phases （A group） , 60 cases with chronic cot pulmonale in paracmasis （B group） and 65 cases normal （C group）. Results Compared with C group, The indicatrix （hs -CRP, WBC and ESR） of patients with chronic eor pulmonale were significantly higher, and compared with B group, these indicatfix were significantly higher. The position rate of hs - CRP in senium patients with chronic cor pulmonale was 93.8%, and was higher than that of the other indicatrix. Conclusion The result was imply hs - CRP to conduce to early diagnosis and therapeutic efficacy index of chronic cot pulmonale in acute exacerbation phases.