慢性肾功能不全医院感染临床分析

Clinical observation on nosocomial infection in the patients with chronic renal failure

目的分析慢性肾功能不全患者医院感染情况,了解其临床特点,为临床防治提供依据。方法对2003-01～2007-12发生医院内感染的慢性肾功能不全患者64例、72例次进行回顾性分析。结果慢性肾功能不全患者医院感染率为8.4%,以糖尿病肾病发生率最高(40.6%),感染部位呼吸道占首位(58.3%),病原菌以革兰氏阴性菌为主(63.0%),同时与慢性肾功能不全程度、血浆白蛋白水平、营养状况、住院时间等相关。结论慢性肾功能不全患者医院感染率高,其中糖尿病肾病最高,感染部位以呼吸道感染占首位。缩短住院时间、加强护理、改善营养、治疗合并症可减少医院感染的发生。

Objective To investigate the clinic features of nosocomial infection in patients with chronic renal failure （CRF）. Methods Sixty-four patients with CRF from 2003 to 2007 were retrospectively analyzed. Results Nosocomial infection rate in CRF was 8. 4 %. It occurred mainly in the cases complicated with diabetic nephropathy （g0. 6% ）. The dominant infectious location was respiratory tract （58.3%）. Gram-negative bacilli were the dominaut bacteria in the infections （63.0%）. The nosocomial infection showed a close relationship with the severity of CRF, the level of serum albumin, nutrition and duration in hospital. Conclusion Nosocomial infection rate in pa- tients with CRF is high, especially in the patients complicated with diabetic nephrepathy. It can be reduced by shortening duration in hospital, improving medical care and nutrition condition, and dealing with complications effectively.