苏州市出生缺陷干预效果分析

Analysis on intervention effect of birth defects in Suzhou

目的:分析探讨出生缺陷的相关因素及干预效果,为进一步减少出生缺陷的发生、提高出生人口素质提供依据。方法:对苏州市2003～2008年出生缺陷个案进行回顾性调查,将出生缺陷发生率等定量资料进行统计分析,定性资料归纳分析。结果:6年来苏州市出生缺陷发生率从2003年的9.61‰下降到2008年的7.36‰。<20岁及>34岁年龄组妇女分娩缺陷儿的风险明显增加,男胎出生缺陷的发生率明显高于女胎。结论:苏州市出生缺陷干预工程的实施,有效地降低了新生儿出生缺陷的发生率,进一步提高了出生人口素质。在提高产前筛查及诊断、完善二级预防的基础上,应全面开展一级预防,积极开展三级预防。

Objective： To analyze the related factors and intervention effect of birth defects, and provide a basis for decreasing the incidence of birth defects and increasing the quality of birth population. Methods： Birth defect cases from 2003 to 2008 in Suzhou were in- vestigated retrospdctively, statistical analysis of incidence of birth defects was conducted ; and qualitative data was summarized. Results ： The incidence of birth defects in Suzhou decreased from 9. 61%o in 2003 to 7.36‰ in 2008. The risk of delivering birth defects infants in pregnant women 〈 20 years or 〉 34 years increased significantly, the incidence of birth defects of male fetuses was higher than that of female fetuses. Conclusion ： The implementation of birth defect interference program in Suzhou has reduced the incidence of birth defects in neonates, which further improves the quality of birth population. On the basis of increasing prenatal screening and perfecting secondary preven- tion, primary prevention should be carried out comprehensively and tertiary prevention should be carried out actively.