皮质下缺血性血管性痴呆

Subcortical ischemic wscular dententia

皮质下缺血性血管性痴呆是血管性认知障碍的一个亚型，以腔隙性梗死和深部白质改变为主要病理学特征，临床上主要表现为执行功能受损。伴皮质下梗死和白质脑病的常染色体显性遗传性腑动脉病为无阿尔茨海默病的单纯皮质下血管性痴呆研究提供了机会。目前尚缺乏诊断皮质下缺血性血管性痴呆的金标准，影像学检查在其诊断中发挥着重要作用，而治疗则必须首先考虑控制血管危险因素，尤其是高血压。

Subcortical ischemic vascular dementia is a subtype of vascular cognitive impairment. Its major pathological features are lacunar infarcts and deep white matter changes, and its major clinical manifestation is executive function impairment. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy （CADASIL） provides an opportunity for the study of pure subcortical ischemic vascular dementia in the absence of Alzheimer＇s disease. There is currently lack of the gold standard for diagnosing subcortical ischemic vascular dementia. Imaging examination plays an important role in its diagnosis, while the treatment must first consider the control of vascular risk factors, especially hypertension.