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sTREM－1在诊断新生儿细菌感染性疾病中的作用 被引量：1

sTREM -1 ： a new diagnostic marker of serious bacterial infection in neonate
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摘要 髓样细胞触发受体（triggering receptors expressed on myeloid cells,TREM）是新近发现的受体家族，其中TREM-1与炎症反应有关，而其可溶性形式sTREM-1与多种炎症疾病密切相关。在新生儿细菌感染性疾病中sTREM-1也呈高表达，有望成为诊断新生儿细菌感染的新指标。 The triggering receptor expressed on myeloid cells （TREM） -1 is a recently identified molecule involved in the inflammatory response. It belongs to the immunoglobulin supeffamily,it was repotted that it has relation with inflammatory response mediated by several microbial components, besides its soluble form was observed and identified at significant levels in bacterial infection of neonate. So it may become a valuable diagnostic marker of serious bacterial infeetion in neonate.
作者 唐文娟(综述) 黄绮薇(审校)
机构地区 上海交通大学附属儿童医院
出处 《国际儿科学杂志》 2010年第2期122-125,共4页 International Journal of Pediatrics
关键词 可溶性髓样细胞触发受体-1 新生儿 感染 sTREM- 1 Neonate Infection
分类号 R446.61 [医药卫生—诊断学]
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参考文献25

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同被引文献14

  • 1樊寻梅.儿科感染性休克(脓毒性休克)诊疗推荐方案[J].中华儿科杂志,2006,44(8):596-598. 被引量：205
  • 2An G, Namas RA, Vodovotz Y. Sepsis: from pattern to mechanism and back [J]. Crit Rev Biomed Eng, 2012, 40(4): 341-351.
  • 3Bouchon A, Facchetti F, Weigand MA, et al. TREM-I amplifies in- flammation and is a crucial mediator of septic shock [J]. Nature, 2001, 410(6832): 1103-1107.
  • 4Jiyong J, Tianeha H, Wei C, ct al. Diagnostic value of the soluble triggering receptor expressed on myeloid cells-1 in bacterial infec- tion: a meta-analysis [J]. Intensive Care Med, 2009, 35(4): 587-595.
  • 5Barati M, Bashar FR, Shahrami R, et al. Soluble triggering receptor expressed on myeloid cells 1 and the diagnosis of sepsis [J]. J CritCam, 2010, 25(2): 362.
  • 6Ricdel S. Procalcitonin and the role of biomarkers in the diagnosis and management of sepsis [J]. Diagn Microbiol Infect Dis, 2012, 73 (3): 221-227.
  • 7Levy MM, Fink MP, Marshall JC, et al. 2001 SCCM/ESICM/ACCP/ ATS/SIS International Sepsis Def'mitions Conference [J]. Crit Care Mcd, 2003, 31(4): 1250-1256.
  • 8Vasiljevi B, Antonovi O, Maglajli(-Djuki S, et al. The serum lev- el of C-reactive protein in neonatal sepsis [J]. Srp Arh Celok Lek, 2008, 136(5-6): 253-257.
  • 9Dupont C, Rodenbach J, Flachaire E. The value of C-reactive pro- tein for postoperative monitoring of lower limb arthroplasty [J]. Ann Re, adapt Med Plays, 2008, 51(5): 348-357.
  • 10林小玲,江山平.严重脓毒症与脓毒性休克的若干治疗进展[J].临床内科杂志,2009,26(7):440-443. 被引量：4

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国际儿科学杂志
2010年 第2期

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