摘要
硫化氢（H2s）是继一氧化氮和一氧化碳之后发现的气体信号分子，有着广泛的生物学活性。H2s在炎症细胞、炎症介质、血管张力和信号通路等方面参与了炎症反应的各个环节，发挥双向的调节作用，包括抗炎和促炎作用。不同的动物炎症模型中H2s所起的作用不同。深入探讨H2s在炎症中的效应及作用机制，可为炎症疾病的治疗提供新的防治措施。
Hydrogen sulfide （H2 S） was considered as the third gasotransmitter, along with mtne oxide and carbon monoxide, with extensively biological activities. Considerable evidence showed that H2S was involved in inflammatory processes such as in inflammatory cells, inflammatory mediates, vascular tension and signaling pathways. Previous studies suggested H2S played a bidirectional role in regulating inflammation including proand anti-inflananatory actions due to different animal models. Further study about the role and mechanism of H2S in inflammation will contribute to efficient prevention and treatment for inflammatory diseases.
出处
《国际儿科学杂志》
2010年第2期212-214,共3页
International Journal of Pediatrics
基金
温州市科技计划项目（Y20090031）
关键词
硫化氢
炎症
气体信号分子
Hydrogen sulfide
Inflammation
Gasotransmitter
