新疆地区不同人群HCV感染现状分析

Detection of Hepatitis C Virus (HCV)in Different Patients in Xinjiang

应用第二代酶联免疫试验(ELISA)对新疆地区3012例不同人群进行丙型肝炎病毒抗体(抗—HCV)检测。结果显示:抗—HCV抗体的总阳性率为10.82％(326/3012)。其中以肾透析患者阳性率最高占86.57％,其次为输血、有手术史病人,阳性率为79.34％,吸毒者阳性率为61.54％。我们对326例抗HCV阳性标本又进行了HBsAg、ALT、AST和GGT检测,发现HBsAg阳性率为19.33％,ALT、AST和GGT异常率分别为67.80％、61.96％、48.16％。提示:输血是传播丙型肝炎病毒的重要途径之一,并丙型肝炎患者一般都伴有肝功能异常。为此,通过检测丙型肝炎病毒抗体和ALT、AST、GGT来筛选献血员对减少丙型肝炎的发生起了重要作用。

; purpovse To obtain the infection rate of HCV in different patient, methods In this studies,there are 3012 patients, They are divided into 4 groups. They are 3012 patients performed bynephrology dialysis (Gj), blood donor and the operated patients (G2) , Drng addict (G3) respectively. HCVwere detitected with the modern ELISA. results (1) In 3012 patitents ,the total positive rate of HCV is 10. 82% (326/3012). The possitive rate of G,.G2and G3 is 86. 50%,79. 34% and 61. 54%, respertively. (2)In 326 patients with HCV, We deteded HBsAg found the positive rate is 19. 33%. (3) The positive rate is 67. 80%, 61. 96% and 48. 16% respectively using ALT, AST and GGT,conclusions (1) Blood tranfusion is one of the important way of spreading HCV and the patient with HCV often hurt them hepaticfunction population. (2) It is necessery for reducing the infection rate of HCV in the blood donors using ALT, AST and GGT to detect the HCV.