健康体检人群高尿酸血症及代谢综合征患病分析

Prevalence of hyperuricemia and metabolic syndrome in health check-up subjects

目的了解天津市部分成年健康体检人群中高尿酸血症(HUA)及代谢综合征(metabolic syndrome,MS)的患病情况,为今后开展防治策略提供科学依据。方法HUA参照临床诊断标准,MS按照2004年中华医学会推荐的MS诊断标准(CDS标准),对18 100名健康体检人员的检验结果进行分析。结果该人群HUA总患病人数为2 294人,总患病率为12.76%,其中男性696人,患病率为10.90%;女性1 598人,患病率为13.64%,女性患病率高于男性(P<0.05);HUA合并MS总患病人数为902人,总体患病率为4.99%,其中男性339人,患病率为5.31%;女性563人,患病率为4.81%,男性患病率高于女性(P<0.05);HUA患病率随代谢紊乱的加重呈增高趋势(P<0.05)。结论该人群具有较高的HUA及MS患病率,因此,应尽早筛查和发现HUA和MS高危人群,并及时进行综合防治。

Objective To learn prevalent characteristics of hyperuricemia（HUA）and metabolic syndrome（MS）in the adults having health check-up in Tianjin city for making strategy for the control of the diseases.Methods The health check-up results of 18 100 examinees were analyzed according to the diagnostic criteria of HUA and MS recommended by Chinese Medical Association.Results The total number of HUA was 2 294 with 696 males and 1 598 females.The prevalence of HUA was 12.74%（10.90% in the male,13.64% in the female）.The HUA prevalence of the females was higher than that of the males（P0.05）.The total number of patients with HUA and MS was 902（339 males,563 females）.The comorbidity rate of HUA and MS was 4.99%（5.31% in the male,4.81% in the females）.The comorbidity rate of the males was higher than that of the females（P0.05）.There was an increasing trend in the prevalence of HUA with the increase of metabolic disorder（P0.05）.Conclusion The prevalences of HUA and MS in the population are high and it is necessary to do screening and comprehensive intervention among the population with high risk of HUA and MS.