多层螺旋CT诊断急性肠系膜上动脉栓塞的实验研究

Experimental study of MSCT diagnosis of acute superior mesenteric artery embolism

目的建立犬急性肠系膜上动脉栓塞的动物模型,通过多层螺旋CT血管成像(MSCTA)检查,并与DSA对照,探讨MSCTA对急性肠系膜上动脉栓塞的诊断价值。方法①术前对选用的实验动物进行MSCTA检查。②应用Seld ing技术,经犬股动脉穿刺成功后对肠系膜上动脉进行选择性血管造影;之后将导管选择性插入肠系膜上动脉,以无水乙醇栓塞其远端主干,建立犬急性肠系膜上动脉栓塞模型;随之再次进行肠系膜上动脉选择性血管造影。③术后再次对实验动物进行MSCTA检查。④利用工作站对CT图像进行后处理,选择最佳后处理方式。⑤分析术前及术后DSA和CT图像,进行对照。结果实验动物均成功建立急性肠系膜上动脉栓塞模型;DSA和MSC-TA均能清晰显示肠系膜上动脉及其内栓塞情况。结论采用Seld inger技术,利用无水乙醇栓塞可以建立急性肠系膜上动脉栓塞模型;MSCTA可以诊断急性肠系膜上动脉栓塞。

Objective To evaluate the diagnostic value of multi-slice spiral CT（MSCT） examination in acute superior mesenteric artery embolism after establishing canine＇s models.Methods ①MSCT angiography（MSCTA） was performed before embolization.②After successfully punctured into the femoral artery through seldinger＇s technique,DSA was performed;then,absolute ethanol was selectively injected into the superior mesenteric artery（SMA） for embolization and DSA followed.③MSCTA was performed after embolization.④The MSCTA images were reconstructed on work-station by the best techniques.⑤The images of DSA and MSCTA were analyzed and contrasted.Results The canine＇s models of acute superior mesenteric artery embolism were successfully established.Both DSA and MSCTA examination displayed superior mesenteric artery and its embolism clearly.Conclusion The models of acute superior mesenteric artery embolism can be established by seldinger＇s technique;MSCTA examination can diagnose acute superior mesenteric artery embolism early.