期刊文献+

异甘草酸镁联合腺苷蛋氨酸治疗胆汁淤积性肝炎30例分析 被引量:4

原文传递
导出
摘要 目的观察异甘草酸镁联合腺苷蛋氨酸治疗胆汁淤积性肝炎患者的疗效及安全性。方法将58例胆汁淤积性肝炎患者按照随机数字表法分成两组,治疗组30例应用异甘草酸镁100mg,静脉滴注,1次/d;对照组28例应用复方甘草酸苷120mg,静脉滴注,1次/d。两组同时应用腺苷蛋氨酸1g,静脉滴注,1次/d。两组总疗程均为90d。结果治疗组总有效率80.0%(24/30),对照组64.3%(18/28),两组比较差异有统计学意义(P〈0.05),且治疗组血清总胆红素恢复显著优于对照组(P〈0.01)。结论异甘草酸镁联合腺苷蛋氨酸治疗胆汁淤积性肝炎疗效显著,不良反应小。
作者 李琪波
出处 《中国医师进修杂志》 2010年第7期58-59,共2页 Chinese Journal of Postgraduates of Medicine
  • 相关文献

参考文献3

二级参考文献89

  • 1[9]Uesugi T, Froh M, Arteel GE, Bradford BU, Wheeler MD, Gabele E, Isayama F, Thurman RG. Role of lipopolysaccharidebinding protein in early alcohol-induced liver injury in mice. J Immunol2002; 168:2963-2969
  • 2[10]Faggioni R, Fantuzzi G, Gabay C, Moser A, Dinarello CA, Feingold KR, Grunfeld C. Leptin deficiency enhances sensitivity to endotoxin-induced lethality. Am J Physiol 1999; 276: R136-R142
  • 3[11]Li Z, Yang S, Lin H, Huang J, Watkins PA, Moser AB, Desimone C, Song XY, Diehl AM. Probiotics and antibodies to TNF inhibit inflammatory activity and improve nonalcoholic fatty liver disease. Hepatology 2003; 37:343-350
  • 4[12]Hug H, Strand S, Grambihler A, Galle J, Hack V, Stremmel W,Krammer PH, Galle PR. Reactive oxygen intermediates are involved in the induction of CD95 ligand mRNA expression by cytostatic drugs in hepatoma cells. J Biol Chem 1997; 272:28191-28193
  • 5[13]Feldstein AE, Canbay A, Angulo P, Taniai M, Burgart LJ, Lindor KD, Gores GJ. Hepatocyte apoptosis and fas expression are prominent features of human nonalcoholic steatohepatitis.Gastroenterology 2003; 125:437-443
  • 6[14]American Gastroenterological Association medical position statement: nonalcoholic fatty liver disease. Gastroenterology 2002; 123:1702-1704
  • 7[15]Andersen T, Gluud C, Franzmann MB, Christoffersen P. Hepatic effects of dietary weight loss in morbidly obese subjects.J Hepatol1991; 12:224-229
  • 8[16]Luyckx FH, Scheen AJ, Desaive C, Dewe W, Gielen JE, Lefebvre PJ. Effects of gastroplasty on body weight and related biological abnormalities in morbid obesity. Diabetes Metab 1998;24:355-361
  • 9[17]Drenick EJ, Simmons F, Murphy JF. Effect on hepatic morphology of treatment of obesity by fasting, reducing diets and small-bowel bypass. N Engl J Med 1970; 282:829-834
  • 10[18]Cox KL, Burke V, Morton AR, Beilin LJ, Puddey IB. Independent and additive effects of energy restriction and exercise on glucose and insulin concentrations in sedentary overweight men. Am J Clin Nutr 2004; 80:308-316

共引文献108

同被引文献76

引证文献4

二级引证文献24

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部