婴幼儿轮状病毒肠炎的心肌酶谱变化

Changes of serum myocardial enzyme in infants with rotavirus enteritis

目的探讨婴幼儿轮状病毒(RV)肠炎时心肌酶谱的变化。方法对2005年9月至2007年9月在我院住院的腹泻病患儿,用胶体金法进行粪便轮状病毒抗原检测,用连续检测法测定血清心肌酶的水平。结果①RV肠炎组与对照组比较心肌酶谱明显升高(P(0.01);②轻度脱水组肌酸激酶(CK),肌酸激酶同工酶(CK-MB)均明显高于无脱水组(P(0.01),而中度脱水组各项指标均明显高于轻度脱水组(P(0.01)。③RV肠炎般心肌损害患儿经给与1,6-二磷酸果糖治疗后,心肌酶基本恢复正常。结论轮状病毒感染可致心肌损害,对轮状病毒肠炎患儿应警惕心肌损害,治疗同时注意心肌保护。

Objective To study the changes of myocardial enzymes in infants with rotavirus diarrhea. Methods Stool rotavirus antigen was detected by colloidal gold method and serum myocardial enzymes were detected with continuous detection in infant patients with diarrhea, hospitalized at our hospital from September 2005 to September. 2007. Results ①Compm＇ed with the control group, the level of myocardial enzyme significantly increased （ P 〈 0.01 ） in RV enteritis group; ② CK, CK - MB were significantly higher in mild dehydration group than those in group without dehydration （ P 〈0.01 ）, while the indicators in moderate dehydration group were significantly higher than those in mild dehydration group （ P 〈 0.01 ）.③ After 1,6 - diphosphate treatment, myocardial enzymes returned to normal in RV enteritis infants accompanied by myocardial damage. Conclusion Myocardial damage can be caused by rotavirus infection. Attention should be paid to myocardial damage and its treatment in infants with rotavirus diarrhea.