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C反应蛋白在糖尿病临床中的应用 被引量:3

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摘要 1930年,Tillet和Francis首次在急性大叶性肺炎患者血清中发现了一种能在钙离子存在时与肺炎球菌细胞壁中荚膜多糖(C多糖)形成复合物的物质,并命名为C反应蛋白(C-RP)。C-RP分子量为115KD,分子结构为5个相同的亚基依靠非共价键形成的环状五聚体,是肝脏合成的急性时相反应蛋白,在动脉粥样硬变处、肾脏、神经元及空泡巨噬细胞中也有合成。目前有关C—RP在临床中应用的报道很多,本文综述C-RP在糖尿病诊断中的应用。
出处 《中国糖尿病杂志》 CAS CSCD 北大核心 2010年第3期235-236,共2页 Chinese Journal of Diabetes
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