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新辅助化疗在晚期卵巢癌患者手术治疗中的作用 被引量:2

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摘要 目的探讨新辅助化疗在晚期卵巢癌患者手术治疗中的作用。方法选择晚期上皮性卵巢癌患者44例,其中,新辅助化疗组22例与传统治疗组22例。结果新辅助化疗组与传统治疗组比较,临床分期差异无统计学意义(P=0.056)、年龄偏大(P=0.0476)、生活状态差(P=0.0022)的情况下,最终获得了理想的细胞减灭术;新辅助化疗后较化疗前平均肿瘤体积缩小(P=0.0024)、腹腔积液量减少(P=0.0000)、CA-125值降低(P=0.0060)、生活状态改善(P=0.0000),肿瘤血供较化疗前明显减少、肿块松动、大网膜饼变薄,新辅助化疗后行肿瘤细胞减灭术提高了原发灶及转移灶的切净程度,减少了术中出血、缩短了手术时间、重症监护日及住院日,与传统治疗组比较差异有统计学意义(P〈0.05)。结论新辅助化疗使已经丧失手术可能的晚期患者又重新获得了手术机会,为理想的肿瘤细胞减灭术创造了条件。
作者 李峰 许志平
出处 《肿瘤研究与临床》 CAS 2010年第2期128-130,共3页 Cancer Research and Clinic
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同被引文献31

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