2,2’-双[4-(4-氨基苯氧基)苯基]丙烷的制备方法

Synthesis Method of 2,2'-bis[4-(4-aminophenoxy)phenyl]propane

介绍了以2,2’-双(4-羟基苯基)丙烷、对氯硝基苯,碱金属碳酸盐或碱金属氢氧化物为原料,在合适的溶剂中合成2,2’-双[4-(4-硝基苯氧基)苯基]丙烷,再经不同还原方法制备2,2’-双[4-(4-氨基苯氧基)苯基]丙烷。并从反应工艺条件、产品收率、产物纯度、是否适合规模化生产等方面阐述了制备2,2’-双[4-(4-氨基苯氧基)苯基]丙烷方法的优缺点。通过比较、分析指出了2,2’-双[4-(4-氨基苯氧基)苯基]丙烷的研究和发展方向。

2,2＇-bis[ 4-（4-nitrophenoxy）phenyl ]propane is synthesized by reaction among alkali metal carbonate or alkali metal hydroxides, 2,2- bis（4-hydroxyphenyl）propane and p-chloro nitrobenzene in a suitable solvent. Then 2,2＇-bis[4-（4-nitroophenoxy）phenyl]propane is reduced into 2, 2＇-bis [4-（4-aminophenoxy）phenyl]propane by different methods. The advantage and disadvantage of some production methods are presented from many aspects, such as the reaction conditions, yield of product, purity and whether it is suitable for large-scale production, etc. The research and development trend of 2,2＇-bis[4-（4-aminophenoxy）phenyl]propane are also pointed out.