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亲环素A在常见风湿性疾病中的研究进展 被引量:3

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摘要 亲环素A是免疫抑制剂环孢素在细胞内的结合蛋白,具有肽酰脯氨酰顺反异构酶活性,参与蛋白质折叠,还可作为细胞因子分泌到胞外通过调节相应的信号通路而参与炎症细胞的趋化、炎症细胞因子的表达及血管内皮细胞的炎症调控等,产生促炎效应,可能在多种风湿性疾病(风湿病)的发病过程中发挥重要作用。该文主要针对亲环素A在常见风湿病中的作用研究进展情况作一综述。
出处 《新医学》 2010年第2期131-133,共3页 Journal of New Medicine
基金 广东省科技计划(2008B030301039)
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参考文献20

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共引文献7

同被引文献37

  • 1张缪佳,刘晓华,柯瑶,王艳艳,谈文峰,顾镭,王嫱,季晓辉.系统性红斑狼疮患者亲环素A表达异常及其意义的初步探讨[J].中华风湿病学杂志,2005,9(11):698-700. 被引量:6
  • 2肖征宇.强直性脊柱炎的治疗进展[J].中国实用内科杂志,2007,27(1):71-74. 被引量:22
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