血清前降钙素对儿科脓毒症的早期诊断作用

The early diagnosis value of serum procalcitonin to children's sepsis

目的:与其他常用临床指标相比,评价血清前降钙素对于儿童脓毒症的早期诊断价值。方法:随机选取2008年1～12月在PICU治疗的患儿37例,根据ACCP/SCM会议的诊断标准,将患儿分为三组,脓毒症组,非感染组,病毒感染组,于入院第1天对患儿进行血清前降钙素水平测定,并测定体温、血清CRP、外周血白细胞计数。结果:脓毒症组患儿有较高的血清前降钙素(PCT)水平,而其他临床指标:体温、外周血白细胞计数在组间无显著差别,血清CRP在三组间有数据重叠。结论:与常规指标相比(体温、血清CRP、外周血白细胞计数),脓毒症患儿血清PCT水平明显升高,因而,血清PCT可以用于早期诊断严重感染和脓毒症。

Objective： Compared with other clinical index,evaluated the early diagnosis value of serum procalcitonin to children＇s sepsis. Methods： Randomly selecting 37 cases of children who entered into PICU treatment from January to December 2008. According to the diagnostic criteria of ACCP/SCM Conference, these children were divided into three groups,sepsis group, non-infected group and virus infection group. They were tested serum procalcitonin levels, measured body temperature,serum CRP, peripheral blood white blood cell count individually on the first day of hospitalization. Results： Group of children with sepsis had higher levels of serum PCT, while there were no differences in other clinical indicators such as body temperature, peripheral white blood cell count.And serum CRP data had overlapped phenomenon among the three groups. Conclusion： Compared with conventional indicators（body temperature,CRP,peripheral blood white blood cell count）,serum PCT levels in children with sepsis is significantly increased, hence, serum PCT can be used for early diagnosis of severe infection and sepsis.