摘要
目的:评价肝素的使用时机对急性心肌梗死再灌注的影响。方法:收治住院符合ST段抬高的急性心肌梗死溶栓标准的患者66例,将其分为观察组33例和对照组33例。均给予尿激酶1500000U加入100ml0.9%氯化钠溶液中,于30min内静脉输注溶栓。观察组于溶栓前即刻给予普通肝素5000U静推。结果:观察组尿激酶溶栓后再通率为87.88%,对照组溶栓后再通率为66.67%,两者比较,差异有统计学意义(P<0.05)。结论:尿激酶溶栓前即刻静脉输注肝素能显著提高冠状动脉血管再通率,改善患者预后,不会增加临床出血的危险。
Objective: To evaluate the effects of the use of timing of heparin in acute myocardial infarction reperfusion. Methods: Patients treated in line with ST-segment elevation acute myocardial infarction cases of the standard,66 cases were divided into 33 cases of the observation group and the control group of 33 cases. 1 500 000 U of urokinase were given by adding 100 ml normal saline in 30 minutes intravenous infusion thrombolysis.Immediately before the observation group was given thrombolytic therapy given 5 000 U unfractionated heparin bolus. Results: The group of urokinase patency rate was 87.88%,the control group pass rate was 66.67%. After comparision, the difference was significant(P〈0.05). Conclusion: Immediately before thrombolysis by intravenous infusion of heparin significantly increase the rate of coronary artery recanalization and improve the prognosis of patients, not to increase the clinical risk of bleeding.
出处
《中国当代医药》
2010年第7期54-55,共2页
China Modern Medicine
关键词
急性心肌梗死
再灌注
肝素
Acute myocardial infarction
Reperfusion
Heparin