老年人椎基底动脉血流动力学改变与缺血性脑血管病的关系

Relation between the Changes in Vertebro-Basilar Hemodynamics and Cerebrovascular Ischemic Disease in the Aged

目的：研究缺血性脑血管病与椎基底动脉血流动力学改变的关系。方法：对４２例老年缺血性脑血管病患者颅内外动脉血流速度进行经颅多普勒超声监测分析。结果：（１）椎基底动脉与颈内动脉相比，血流速度降低具有显著性差异（Ｐ＜０．０１）。（２）短暂性脑缺血发作在椎基底动脉血流速度高低范围内均可发作，而脑血栓形成及多发性腔隙性梗死则集中在椎基底动脉低血流速度范围内。（３）椎基底动脉血流速度降低与脑梗死发病率呈正相关（ｒ＝０．９９８３，Ｐ＜０．０５）。结论：椎基底动脉缺血严重的患者有发生脑梗死的高度危险性。

Objective:The purpose of the investigation was to study the relation between the changes in vertebro-basilar blood flow velocity (BFV) and cerebral infarction in the aged.Method:Vertebro-basilar blood flow velocity was detected by transcranial doppler ultrasound in 42 aged with cerebrovascular ischemic disease.Results:(1)The BFV declined in vertebro-basilar artery compared with that in internal carotid artery( P <0.01).(2)Transient ischemic attacks were ranged widely in vertebro-basilar artery with different BFV,cy with lower BFV.(3)The incidence of cerebral infarction was positively correlated with the degree of vertebro-basilar ischemic( r =0.9983, P <0.05).Conclusion:The patients with vetebro-basilar serious ischemic are at higher risk for stroke.