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2型糖尿病中医证型与同型半胱氨酸的相关性研究 被引量:4

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摘要 目的:观察2型糖尿病(T2DM)不同证型与血清同型半胱氨酸(Hcy)的关系,为中医辨证施治提供客观指标。方法:将58名T2DM患者分为阴虚热盛型、气阴两虚型、阴阳两虚型3种本证组及兼痰湿型、兼血瘀型、兼痰湿血瘀型3种兼证组,并选择30名健康志愿者为正常对照组(NC组),所有纳入者以高效液相色谱法测定血清Hcy浓度。结果:T2DM组血清Hcy浓度(13.70±5.96)μmol/L高于NC组(9.31±3.61)μmol/L,2组比较有统计学意义;T2DM各证型组血清Hcy的比较显示,随着证型由阴虚热盛→气阴两虚→阴阳两虚的演变,患者的Hcy逐渐升高,阴阳两虚型组与气阴两虚型组、阴虚热盛型组比较有统计学意义;兼证各组中,Hcy浓度由高到低次序为:兼痰湿血瘀型组>兼血瘀型组>兼痰湿型组>无兼证型组>NC组,有兼证型组与无兼证型组、NC组比较有统计学意义,三兼证型组间比较无统计学意义。结论:T2DM患者存在高Hcy血症,Hcy浓度与中医辨证分型有关。
出处 《江苏中医药》 CAS 2010年第4期28-29,共2页 Jiangsu Journal of Traditional Chinese Medicine
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