大孔强酸性阳离子交换树脂催化合成柠檬酸三丁酯

Synthesis of tributyl citrate catalyzed by macroporous strong acid cationic exchange resin

以大孔强酸性阳离子交换树脂为催化剂,研究了环保型增塑剂柠檬酸三丁酯的合成及分离提纯工艺条件。通过对诸多反应影响因素的考察,得到了最佳反应条件:n(柠檬酸):n(正丁醇)=1:4.5,催化剂用量为20%(以柠檬酸计算),反应温度130℃,酯化率94.3%。研究了反应产物的精制条件,最终得到纯度大于99.5%的产品。

Synthesis of tributyl citrate using macroporous strong acid cationic exchange resin as a nonhomogeneous catalyst was investigated,the optimum reaction parameters were found as：citric acid to butanol molar ratio of 1：4.5,catalyst amount of 20% citric acid mass,reaction temperature of 130 ℃,under which the esterification yield was above 94.3%.The reaction product purification was also investigated and the purity of purified tributyl citrate was higher than 99.5%.