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绿原酸磁性印记聚合微球的制备与表征 被引量：2

Synthesis and Evaluation of Magnetic Molecularly Imprinted Polymer Microspheres of Chlorogenic Acid
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摘要 以Fe_3O_4纳米粒为磁性组分,绿原酸为模板分子,甲基丙烯酸和三羟甲基丙烷三丙烯酸酯分别为功能单体和交联剂,采用多重乳液悬浮聚合法制备了绿原酸磁性印迹聚合微球,并对形态、大小、组成和磁响应性进行了表征.采用静态平衡吸附试验研究了绿原酸磁性印迹聚合微球的吸附性能,发现其对绿原酸表现出较好的吸附特异性,进一步的Scatchard分析表明存在两类不同性能的吸附位点. Magnetic imprinting polymer microspheres （MIPs） were prepared via multiple emulsions suspension polymerization, u＇sing Fe3O4, chlorogenic acid, methacrylic acid （MAA） and trimethylolpropane triacrylate （TRIM） as magnetic component, template molecule, functional monomer and cross-linker, respectively. The shape and size, composition and magnetic susceptibility were characterized. Static equilibrium adsorption study showed that MIPs had a better specific absorption property for CGA. Scatchard analysis further showed that two different adsorption sites existed in MIPs.
作者 顾晓红 谢洪平
机构地区 苏州大学药学院
出处 《常熟理工学院学报》 2010年第2期56-59,共4页 Journal of Changshu Institute of Technology
关键词 绿原酸 磁性印迹 表征 吸附性能 chlorogenic acid magnetic imprinting characterization absorption property
分类号 R917 [医药卫生—药物分析学]
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参考文献10

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共引文献11

同被引文献33

  • 1林丽洋,贺英菊,陈艳,莫毅,闫根全.绿原酸-β-环糊精包合物的制备及验证[J].天津药学,2006,18(5):25-27. 被引量：7
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  • 7杨蕊,苏乐群,黄欣.齐墩果酸自微乳的制备及质量评价[J].食品与药品,2008,10(1):40-42. 被引量：6
  • 8韩丽英.光和肥对元宝枫叶中绿原酸质量浓度的影响[J].科技情报开发与经济,2008,18(26):103-105. 被引量：4
  • 9张悦,吴忠斌,陈建明.土荆芥油自微乳化释药系统的体外释药特性研究[J].中国新药杂志,2009,18(14):1364-1368. 被引量：2
  • 10葛建丹,陈媚,宋必卫.绿原酸跨细胞转运机制研究[J].中国药理学通报,2009,25(8):1094-1098. 被引量：13

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二级引证文献8

常熟理工学院学报
2010年 第2期

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