近30年高血压病中医用药规律分析

Analysis on Chinese Medicine Medication of Essential Hypertension in Recent 30 Years

目的对1979～2009年中国期刊全文数据库（CNKI）收录的中医治疗高血压病文献，通过频度分析总结用药特点，以期为临床治疗和研究提供参考。方法对所选文献中符合纳入标准的药物运用Excel表进行收录，然后用SPSS13．0进行频数统计。结果共得药物301种，补虚药、清热药、平肝息风药、活血化瘀药、利水渗湿药、解表药，共占79．16％，常用中药34味；药物归经涉及12个脏腑，主要是肝经、肾经、脾经、心经，共占66．97％；所有药物涉及7种药味，出现的总频次为12584，其中甘、苦、辛共占82．99％。结论高血压病所用药物功效、性味和归经与高血压病的病因、病机密切相关；这些用药特点及规律可为目前高血压病的辨证论治提供参考依据。

Objective To probe the regulation of TCM treatment for essential hypertension by analyzing the frequency of herbs usd in the literature of hypertension TCM treatment included in CNK1 from 1979 to 2009 with a view to provide a reference for the clinical treatment and research. Methods The herbs meeting the inclusion criteria in the selected literature was recorded by using Excel table, and analyzed by using SPSS13.0 statistical software. Results Of the 301 herb medicine, the tonics, heat - clearing, calming liver wind, promoting blood circulation and removing blood stasis, removing dampness and promoting diuresis, diaphoretics totally accounted for 79.16%. The attributive channel of these herbs involved in 12 viscera, in which liver meridian, kidney meridian, spleen meridian, heart meridian accounted for 66.97%. All herbs involved in 7 kinds of herbal flavors, and total appearance frequency of the 7 flavors was 12584, in which sweetish, bitterness, pungent herbs accounted for 82.99%. Conclusion Efficacy, property flavors and attributive channel of herb medicine used for essential hypertension are closely related to the pathogen and pathogenesis. These herbal medication regularity provides a reference for the current syndrome differentiation and treatment of essential hypertension.