雾化吸入高渗盐水沙丁胺醇治疗毛细支气管炎疗效及治疗成本分析

Impact of Hypertonic Saline Combined with Salbutamol Inhalation on the Mild to Moderate Bronchiolitis and its Cost and Effect Analysis

目的:探讨雾化吸入3%NaC l溶液(简称高渗盐水)沙丁胺醇治疗轻、中度毛细支气管炎(简称毛细支气管炎)的卫生经济学效果,为改进毛细支气管炎治疗护理措施提供参考。方法:采取随机对照方法,将143例轻、中度毛细支气管炎患儿分成治疗组和对照组,治疗组73例,雾化吸入高渗盐水1.5 mL+沙丁胺醇2.5 mg,8 h/次直至出院;对照组70例,雾化吸入生理盐水1.5 mL+沙丁胺醇2.5 mg,8 h/次直至出院,比较两组临床咳嗽、喘息及住院时间,计算治疗成本。结果:两组患儿均治愈出院,治疗组疗效及治疗费用明显优于对照组(P<0.05)。结论:雾化吸入高渗盐水沙丁胺醇是治疗毛细支气管炎疗效显著并降低治疗成本的有效措施。

Objective：To investigate the treatment effects of nebulized hypertonic saline （hereinafter referred to as 3% NaCl） combined with salbutamol on mild to moderate bronchiolitis and to analyse the cost in health economics, hence, to provide some references in improving nursing measures. Methods： One hundred and forty-three cases of mild to moderate bronchiolitis children were divided into two groups. The infants received inhalation of 2.5 mg （0.5 mL） salbutamol dissolved in either 4.0 mL normal （0.9%） saline （ control group, n = 70） or 4.0 mL hypertonic （3%） saline （treatment group, n = 73）. Patients in each group received 3 treatments every day, delivered at intervals of 8 hours until discharge. Cough, wheezing, pulmonary physical signs, and the length of hospital stay were recorded and compared. Results： The two groups of patients were cured and discharged from the hospital. Compared with the control group, the curative effect was increased and the length of hospital stay was decreased in the treatment group （P 〈 0.05）. Conclusions ： Inhalation of hypertonic saline solution and salbutamol is a safe and effective therapy to patients with mild to moderate bronchiolitis and it can reduce the cost.