富硒绿茶对小鼠部分免疫功能的影响

目的观察富硒绿茶对小鼠免疫功能的影响。方法昆明系小鼠随机分为对照组、低、中、高剂量组。对照组予蒸馏水,其余各组均予不同浓度的茶叶水灌胃。完成腹腔巨噬细胞吞噬活力测定、溶血空斑、CoA诱导脾淋巴细胞转化、腹腔巨噬细胞吞噬鸡红细胞试验。结果各实验显示,低、中剂量组与对照组差异有统计学意义,高剂量组与对照组则差异无统计学意义。结论富硒绿茶低、中剂量能够显著提高小鼠的免疫功能;高剂量短期内可以增强免疫功能,长期使用则不能增强免疫功能。

Objective To observe the effects of the selenium-enriched green tea on the immune function of the mouse. Methods The mouse were randomly divided into the control group, the low-dose group, the middle-dose group, the high-dose group in each experiment. The control group were irrigated with distilled water, and the remaining mouse with the tea water. Sub-peritoneal rnacrophage phagocytosis dynamic tests, hemolytic plaque tests, CoA-induced mouse spleen lymphocyte transformation tests, macrophage phagocytosis of chicken red blood cell tests were complished in the respective division. Results All tests show： there is significant difference between the low-dose group, the middle-dose group and the control group,but there is no significant difference between the high-dose group and the control group. Conclusion the low-dose and the middle-dose Se-rich green tea can significantly improve the immune function of the mouse; the high-dose Se-rich green tea can enhance the immune function in the short term, however the high-dose can not enhance the immune function in the long term, which may be related to significantly inhibit the weight gain of the mouse.